Integrative analyses identify osteopontin, LAMB3 and ITGB1 as critical pro-metastatic genes for lung cancer.

OBJECTIVE: To explore the key regulatory genes associated with lung cancer in order to reduce its occurrence and progress through silencing these key genes. METHODS: To identify the key regulatory genes involved in lung cancer, we performed a combination of gene array and bioinformatics analyses to...

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Bibliographic Details
Main Authors: Xiao-Min Wang, Jing Li, Ming-Xia Yan, Lei Liu, De-Shui Jia, Qin Geng, He-Chun Lin, Xiang-Huo He, Jin-Jun Li, Ming Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3575388?pdf=render