Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP

Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP

Abstract The X-chromosome linked inhibitor of apoptosis (XIAP) is a multidomain metalloprotein involved in caspase inhibition and in copper homeostasis. It contains three zinc-binding baculoviral IAP repeats (BIR) domains, which are responsible for caspase interaction. Recently, it has been suggeste...

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Bibliographic Details
Main Authors: Meng-Meng Hou, Panagis Polykretis, Enrico Luchinat, Xiao Wang, Shen-Na Chen, Hui-Hui Zuo, Yin Yang, Jia-Liang Chen, Yansheng Ye, Conggang Li, Lucia Banci, Xun-Cheng Su
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-16723-5

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https://doi.org/10.1038/s41598-017-16723-5

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