Maturation of the Acute Hepatic TLR4/NF-κB Mediated Innate Immune Response Is p65 Dependent in Mice

Compared to adults, neonates are at increased risk of infection. There is a growing recognition that dynamic qualitative and quantitative differences in immunity over development contribute to these observations. The liver plays a key role as an immunologic organ, but whether its contribution to the...

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Bibliographic Details
Main Authors: Miguel A. Zarate, Leanna M. Nguyen, Robyn K. De Dios, Lijun Zheng, Clyde J. Wright
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
LPS
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01892/full