Microarray amplification bias: loss of 30% differentially expressed genes due to long probe – poly(A)-tail distances

Microarray amplification bias: loss of 30% differentially expressed genes due to long probe – poly(A)-tail distances

<p>Abstract</p> <p>Background</p> <p>Laser microdissection microscopy has become a rising tool to assess gene expression profiles of pure cell populations. Given the low yield of RNA, a second round of amplification is usually mandatory to yield sufficient amplified-RNA...

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Bibliographic Details
Main Authors: Timens Wim, Boezen H Marike, Blokzijl Tjasso, Gibcus Johan H, te Meerman Gerard J, Boelens Mirjam C, Postma Dirkje S, Groen Harry JM, van den Berg Anke
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/277

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http://www.biomedcentral.com/1471-2164/8/277

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