Microarray amplification bias: loss of 30% differentially expressed genes due to long probe – poly(A)-tail distances
<p>Abstract</p> <p>Background</p> <p>Laser microdissection microscopy has become a rising tool to assess gene expression profiles of pure cell populations. Given the low yield of RNA, a second round of amplification is usually mandatory to yield sufficient amplified-RNA...
Main Authors: | Timens Wim, Boezen H Marike, Blokzijl Tjasso, Gibcus Johan H, te Meerman Gerard J, Boelens Mirjam C, Postma Dirkje S, Groen Harry JM, van den Berg Anke |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-08-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/8/277 |
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