Stress-induced locomotor sensitization to amphetamine in adult, but not in adolescent rats, is associated with increased expression of ΔFosB in the nucleus accumbens.

While clinical and pre-clinical evidence suggests that adolescence is a risk period for the development of addiction, the underlying neural mechanisms are largely unknown. Stress during adolescence has a huge influence on drug addiction. However, little is known about the mechanisms related to the...

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Bibliographic Details
Main Authors: Paulo Eduardo Carneiro de Oliveira, Rodrigo Molini Leão, Paula Cristina Bianchi, Marcelo Tadeu Marin, Cleopatra Silva Planeta, Fabio Cardoso Cruz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00173/full