Impaired Phagocytosis in Dendritic Cells From Pediatric Patients With Type 1 Diabetes Does Not Hamper Their Tolerogenic Potential

Impaired Phagocytosis in Dendritic Cells From Pediatric Patients With Type 1 Diabetes Does Not Hamper Their Tolerogenic Potential

Type 1 diabetes (T1D) is prompted by defective immunological tolerance, an event in which dendritic cells (DCs) are crucial as immune response orchestrators. In fact, they contribute to maintaining tolerance to self-antigens, but they can also prompt an immunogenic response against them, leading to...

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Bibliographic Details
Main Authors: Silvia Rodriguez-Fernandez, Marta Murillo, Adrian Villalba, David Perna-Barrull, Mary Cano-Sarabia, Laia Gomez-Muñoz, Eva Aguilera, Daniel Maspoch, Federico Vazquez, Joan Bel, Marta Vives-Pi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
immune tolerance
type 1 diabetes
phagocytosis
autoimmunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02811/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02811/full

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