An Aptamer-Based Antagonist against the Receptor for Advanced Glycation End-Products (RAGE) Blocks Development of Colorectal Cancer

Tumor angiogenesis plays a crucial role in colorectal cancer development. Dysregulation of the receptor for the advanced glycation end-products (RAGE) transmembrane signaling mediates inflammation, resulting in various cancers. However, the mechanism of the RAGE signaling pathway in modulating devel...

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Bibliographic Details
Main Authors: Jihui Zheng, Wenjing Zhu, Fang He, Zhu Li, Na Cai, Hong-Hui Wang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/9958051