A Rare Chromosome Abnormality with der(16)t(1;16)(q12;q11.2) in Blast Crisis of Chronic Myeloid Leukemia

A Rare Chromosome Abnormality with der(16)t(1;16)(q12;q11.2) in Blast Crisis of Chronic Myeloid Leukemia

Although tyrosine kinase inhibitors markedly improve the clinical outcome of chronic myeloid leukemia (CML), blast crisis in CML (CML-BC) still has a poor prognosis. Many chromosomal abnormalities have been reported in CML-BC and may contribute to therapeutic resistance, disease progression, and pro...

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Bibliographic Details
Main Authors: Ryo Yanagiya, Daisuke Ishikawa, Tomomi Toubai, Tsubasa Ichikawa, Naofumi Kawaguchi, Kunie Sugasawa, Kenichi Ishizawa, Soichi Saito
Format: Article
Language:English
Published: Karger Publishers 2020-08-01
Series:Case Reports in Oncology
Subjects:
t(1;16)(q12;q11.2)
genetic instability
chronic myeloid leukemia
blast crisis
additional chromosomal abnormality
Online Access:https://www.karger.com/Article/FullText/509642

Internet

https://www.karger.com/Article/FullText/509642

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