Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice

Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice

Abstract Background Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer’s disease (AD)-like pathological changes. However, it is largely unknown whether BaP exposure participates in the disease progression of AD. Objectives To investigate the effect of BaP e...

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Bibliographic Details
Main Authors: Dan Liu, Yujia Zhao, Yuze Qi, Yun Gao, Dezhen Tu, Yinxi Wang, Hui-Ming Gao, Hui Zhou
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Neuroinflammation
Subjects:
Benzo(a)pyrene
Alzheimer’s disease
Cognition
Amyloid
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-020-01925-y

Internet

http://link.springer.com/article/10.1186/s12974-020-01925-y

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