Evaluation of the Antioxidant Activity of the Marine Pyrroloiminoquinone Makaluvamines

Evaluation of the Antioxidant Activity of the Marine Pyrroloiminoquinone Makaluvamines

Makaluvamines are pyrroloiminoquinones isolated from Zyzzya sponges. Until now, they have been described as topoisomerase II inhibitors with cytotoxic effects in diverse tumor cell lines. In the present work, seven makaluvamines were tested in several antioxidant assays in primary cortical neurons a...

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Bibliographic Details
Main Authors: Eva Alonso, Rebeca Alvariño, Marta Leirós, Jioji N. Tabudravu, Klaus Feussner, Miriam A. Dam, Mostafa E. Rateb, Marcel Jaspars, Luis M. Botana
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Marine Drugs
Subjects:
makaluvamine
Zyzzya
oxidative stress
neurons
marine sponge
nrf2
Online Access:http://www.mdpi.com/1660-3397/14/11/197

Internet

http://www.mdpi.com/1660-3397/14/11/197

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