Splenectomy associated changes in IgM memory B cells in an adult spleen registry cohort.

Asplenic patients have a lifelong risk of overwhelming post-splenectomy infection and have been reported to have low numbers of peripheral blood IgM memory B cells. The clinical value of quantitation of memory B cells as an indicator of splenic abnormality or risk of infection has been unclear. To a...

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Bibliographic Details
Main Authors: Paul U Cameron, Penelope Jones, Malgorzata Gorniak, Kate Dunster, Eldho Paul, Sharon Lewin, Ian Woolley, Denis Spelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3150402?pdf=render