Ionic liquid-promoted green synthesis of biologically relevant diaryl thioethers

This study reports an ionic liquid (IL) promoted green method to obtain diaryl thioethers useful as key intermediates for the synthesis of matrix metalloproteinase (MMP) inhibitors. The synthetic pathway includes a sequential Ullmann reaction and Suzuki cross-coupling. The Ullmann conditions were op...

Full description

Bibliographic Details
Main Authors: Doretta Cuffaro, Felicia D’Andrea, Andrea Mezzetta, Lorenzo Guazzelli, Cinzia Chiappe, Elisa Nuti, Armando Rossello
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2020.1831082