Exposure of E. coli to DNA-methylating agents impairs biofilm formation and invasion of eukaryotic cells via down regulation of the N-acetylneuraminate lyase NanA

Exposure of E. coli to DNA-methylating agents impairs biofilm formation and invasion of eukaryotic cells via down regulation of the N-acetylneuraminate lyase NanA

DNA methylation damage can be induced by endogenous and exogenous chemical agents, which has led every living organism to develop suitable response strategies. We investigated protein expression profiles of Escherichia coli upon exposure to the alkylating agent methyl-methane sulfonate (MMS) by diff...

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Bibliographic Details
Main Authors: Pamela eDi Pasquale, Marianna eCaterino, Angela eDi Somma, Marta eSquillace, Elio eRossi, Paolo eLandini, Valerio eIebba, Serena eSchippa, Rosanna ePapa, Laura eSelan, Marco eArtini, Annateresa ePalamara, Angela eDuilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Microbiology
Subjects:
Virulence
comparative proteomics
Biofilm formation
adaptive response
DNA alkylation
adherent invasive Escherichia coli (AIEC)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00147/full

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