Investigation of the powder flow behaviour of binary mixtures of microcrystalline celluloses and paracetamol

Investigation of the powder flow behaviour of binary mixtures of microcrystalline celluloses and paracetamol

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The flow behaviour of binary mixtures of paracetamol and different grades of microcrystalline celluloses (Avicel® PH101, PH102 and PH200) was studied using a new testing method. The effect of physical characteristics of the powder including tribocharging and the addition of lubricant on the flow pro...

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Bibliographic Details
Main Authors: Ira Soppela, Sari Airaksinen, Matti Murtomaa, Mikko Tenho, Juha Hatara, Heikki Räikkönen, Jouko Yliruusi, Niklas Sandler
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2010-03-01
Series:Journal of Excipients and Food Chemicals
Subjects:
Flowability
powder flow measurement
binary mixture
microcrystalline cellulose
paracetamol
carrier payload
tribocharging
multivariate data analysis
Online Access:https://jefc.scholasticahq.com/article/1140-investigation-of-the-powder-flow-behaviour-of-binary-mixtures-of-microcrystalline-celluloses-and-paracetamol

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https://jefc.scholasticahq.com/article/1140-investigation-of-the-powder-flow-behaviour-of-binary-mixtures-of-microcrystalline-celluloses-and-paracetamol

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