Improving ethanol tolerance of Escherichia coli by rewiring its global regulator cAMP receptor protein (CRP).

A major challenge in bioethanol fermentation is the low tolerance of the microbial host towards the end product bioethanol. Here we report to improve the ethanol tolerance of E. coli from the transcriptional level by engineering its global transcription factor cAMP receptor protein (CRP), which is k...

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Bibliographic Details
Main Authors: Huiqing Chong, Lei Huang, Jianwei Yeow, Ivy Wang, Hongfang Zhang, Hao Song, Rongrong Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585226?pdf=render