UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer

Abstract Background Ubinuclein-2 (UBN2) is a nuclear protein that interacts with many transcription factors. The molecular role and mechanism of UBN2 in the development and progression of cancers, including colorectal cancer (CRC), is not well understood. The current study explored the role of UBN2...

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Main Authors: Ya-li Zhao, Shen-Rong Zhong, Shi-Hong Zhang, Jia-Xin Bi, Zhi-Yuan Xiao, Shu-Yang Wang, Hong-Li Jiao, Dan Zhang, Jun-Feng Qiu, Ling-Jie Zhang, Cheng-Mei Huang, Xiao-Ling Chen, Yan-Qing Ding, Ya-Ping Ye, Li Liang, Wen-ting Liao
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-019-0848-4