Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains

Abstract Background In animals with XY sex chromosomes, X-linked genes from a single X chromosome in males are imbalanced relative to autosomal genes. To minimize the impact of genic imbalance in male Drosophila, there is a dosage compensation complex (MSL) that equilibrates X-linked gene expression...

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Bibliographic Details
Main Authors: Hangnoh Lee, Brian Oliver
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0232-y