Identification of Sox2 and NeuN Double-Positive Cells in the Mouse Hypothalamic Arcuate Nucleus and Their Reduction in Number With Aging

The hypothalamus plays a central role in homeostasis and aging. The hypothalamic arcuate nucleus (ARC) controls homeostasis of food intake and energy expenditure and retains adult neural stem cells (NSCs)/progenitor cells. Aging induces the loss of NSCs and the enhancement of inflammation, including...

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Bibliographic Details
Main Authors: Ayumu Sugiura, Tatsuhiro Shimizu, Takeshi Kameyama, Tomohiko Maruo, Shin Kedashiro, Muneaki Miyata, Kiyohito Mizutani, Yoshimi Takai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.609911/full