Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis

Objective. Syndrome of inappropriate antidiuresis (SIADH) is the predominant cause of hyponatremia, but treatment options are unsatisfying. SGLT2 inhibitors increase urinary glucose excretion with concomitant osmotic diuresis. We therefore hypothesized SGLT2-inhibitors as a novel treatment for SIADH...

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Bibliographic Details
Main Authors: Julie Refardt, Bettina Winzeler, Fabian Meienberg, Deborah R. Vogt, Mirjam Christ-Crain
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/7815690