Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients Is Associated With Underlying Non-Inflamed Tumor Profile

Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients Is Associated With Underlying Non-Inflamed Tumor Profile

Semaphorin 4D (Sema4D) is a glycoprotein that is expressed by several tumors and immune cells. It can function as a membrane bound protein or as a cleaved soluble protein (sSema4D). We sought to investigate the translational potential of plasma sSema4D as an immune marker in plasma of patients with...

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Bibliographic Details
Main Authors: Rania H. Younis, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, Vasileios Ionas Theofilou, Donita Dyalram, Robert A. Ord, Eduardo Davila, Luke J. Tallon, John C. Papadimitriou, Tonya J. Webb, Søren M. Bentzen, Joshua E. Lubek
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
soluble
head and neck squamous cell carcinoma (HNSCC)
Sema4D
immune excluded
real time
IFN-γ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.596646/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.596646/full

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