Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Summary: Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse genetic reference population, to study genetic regulation of variation in antibody response following IAV...

Full description

Bibliographic Details
Main Authors: Kelsey E. Noll, Alan C. Whitmore, Ande West, Mary K. McCarthy, Clayton R. Morrison, Kenneth S. Plante, Brea K. Hampton, Heike Kollmus, Carolin Pilzner, Sarah R. Leist, Lisa E. Gralinski, Vineet D. Menachery, Alexandra Schäfer, Darla Miller, Ginger Shaw, Michael Mooney, Shannon McWeeney, Fernando Pardo-Manuel de Villena, Klaus Schughart, Thomas E. Morrison, Ralph S. Baric, Martin T. Ferris, Mark T. Heise
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720305362

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720305362

Similar Items