Prevalence of the A1555G (12S rRNA) and tRNA Ser(UCN) mitochondrial mutations in hearing-impaired Brazilian patients

Prevalence of the A1555G (12S rRNA) and tRNA Ser(UCN) mitochondrial mutations in hearing-impaired Brazilian patients

Mitochondrial mutations are responsible for at least 1% of the cases of hereditary deafness, but the contribution of each mutation has not yet been defined in African-derived or native American genetic backgrounds. A total of 203 unselected hearing-impaired patients were screened for the presence of...

Full description

Bibliographic Details
Main Authors: Abreu-Silva R.S., Lezirovitz K., Braga M.C.C., Spinelli M., Pirana S., Della-Rosa V.A., Otto P.A., Mingroni-Netto R.C.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Mitochondrial DNA
Hearing impairment
A1555G mutation
tRNA Ser(UCN) mutations
European- and African- Brazilian patients
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200008

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200008

Similar Items