Maternal diet during pregnancy induces gene expression and DNA methylation changes in fetal tissues in sheep

Maternal diet during pregnancy induces gene expression and DNA methylation changes in fetal tissues in sheep

Studies in rats and mice have established that maternal nutrition induces epigenetic modifications, sometimes permanently, that alter gene expression in the fetus, which in turn leads to phenotypic changes. However, limited data is available on the influence of maternal diet on epigenetic modificati...

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Bibliographic Details
Main Authors: Xianyong eLan, Evan C Cretney, Jenna eKropp, Karam eKhateeb, Mary eBerg, Francisco ePeñagaricano, Ronald eMagness, Amy eRadunz, Hasan eKhatib
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Genetics
Subjects:
DNA Methylation
Gene Expression
Pregnancy
Sheep
maternal nutrition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00049/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00049/full

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