A role for bronchial epithelial autotaxin in ventilator-induced lung injury

A role for bronchial epithelial autotaxin in ventilator-induced lung injury

Abstract Background The pathophysiology of acute respiratory distress syndrome (ARDS) may eventually result in heterogeneous lung collapse and edema-flooded airways, predisposing the lung to progressive tissue damage known as ventilator-induced lung injury (VILI). Autotaxin (ATX; ENPP2), the enzyme...

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Bibliographic Details
Main Authors: Ioanna Nikitopoulou, Ioanna Ninou, Nikolaos Manitsopoulos, Ioanna Dimopoulou, Stylianos E. Orfanos, Vassilis Aidinis, Anastasia Kotanidou
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:Intensive Care Medicine Experimental
Subjects:
Mechanical ventilation
Autotaxin
Lung function
Edema
Online Access:https://doi.org/10.1186/s40635-021-00379-7

Internet

https://doi.org/10.1186/s40635-021-00379-7

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