Activation of the KDM5A/miRNA-495/YTHDF2/m6A-MOB3B axis facilitates prostate cancer progression

Activation of the KDM5A/miRNA-495/YTHDF2/m6A-MOB3B axis facilitates prostate cancer progression

Abstract Background Accumulating evidence supports that lysine-specific demethylase 5 (KDM5) family members act as oncogenic drivers. This study was performed to elucidate the potential effects of KDM5A on prostate cancer (PCa) progression via the miR-495/YTHDF2/m6A-MOB3B axis. Methods The expressio...

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Bibliographic Details
Main Authors: Chen Du, Caihong Lv, Yue Feng, Siwen Yu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
KDM5A
microRNA-145
YTHDF2
MOB3B
m6A modification
Prostate cancer
Online Access:http://link.springer.com/article/10.1186/s13046-020-01735-3

Internet

http://link.springer.com/article/10.1186/s13046-020-01735-3

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