Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway
BackgroundLeonurine, a major bioactive component from Herba leonuri, has been shown to exhibit anti-inflammatory and antioxidant effects. The aim of this study was to investigate the effect of leonurine on bone marrow-derived mesenchymal stem cells (BMSCs) as a therapeutic approach for treating oste...
Main Authors: | Bingkun Zhao, Qian Peng, Enoch Hin Lok Poon, Fubo Chen, Rong Zhou, Guangwei Shang, Dan Wang, Yuanzhi Xu, Raorao Wang, Shengcai Qi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-02-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2021.615191/full |
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