Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment

Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment

Recent evidences indicate an important role of tissue inflammatory responses by innate immune cells in allograft acceptance and survival. Here we investigated the role of mast cells (MC) in an acute male to female skin allograft rejection model using red MC and basophil (RMB) mice enabling condition...

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Bibliographic Details
Main Authors: Flavie Ngo Nyekel, Emeline Pacreau, Samira Benadda, Rasha Msallam, Magnus Åbrink, Gunnar Pejler, Jean Davoust, Marc Benhamou, Nicolas Charles, Pierre Launay, Ulrich Blank, Gregory Gautier
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
mast cells
neutrophils
degranulation
skin
transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02690/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02690/full

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