ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency

ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency

<p>Abstract</p> <p>Background</p> <p>The herpes simplex virus type 1 (HSV-1) ICP0 protein is an E3 ubiquitin ligase, which is encoded within the HSV-1 latency-associated locus. When ICP0 is not synthesized, the HSV-1 genome is acutely susceptible to cellular repression....

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Bibliographic Details
Main Authors: Balliet John W, Carr Daniel JJ, Soboleski Mark, Grace Jennifer, Weisend Carla, Halford William P, Imai Yumi, Margolis Todd P, Gebhardt Bryan M
Format: Article
Language:English
Published: BMC 2006-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/3/1/44

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http://www.virologyj.com/content/3/1/44

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