NLRP3 inflammasome activity is upregulated in an in-vitro model of COPD exacerbation.

BACKGROUND:Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized by a progressive and irreversible deterioration of lung function. Exacerbations of COPD have prolonged negative effects on pulmonary function and a major impact on health status and outcomes. NLRP3 infla...

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Bibliographic Details
Main Authors: Noy Nachmias, Sheila Langier, Rafael Y Brzezinski, Matan Siterman, Moshe Stark, Sara Etkin, Avital Avriel, Yehuda Schwarz, Shani Shenhar-Tsarfaty, Amir Bar-Shai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214622