Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex

Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex

Abstract Background Embryonic stem cells (ESCs) are important source of clinical stem cells for therapy, so dissecting the functional gene regulatory network involved in their self-renewal and proliferation is an urgent task. We previously reported that Ddx56 interacts with the core transcriptional...

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Bibliographic Details
Main Authors: Jingwen Wang, Jiahui Liu, Miaoman Ye, Feng Liu, Su Wu, Junjiu Huang, Guang Shi
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Embryonic stem cells
Ddx56
Proliferation
Ribosome assembly
Oct4/Sox2 complex
Cell cycle
Online Access:http://link.springer.com/article/10.1186/s13287-020-01800-w

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http://link.springer.com/article/10.1186/s13287-020-01800-w

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