Sulfite-induced protein radical formation in LPS aerosol-challenged mice: Implications for sulfite sensitivity in human lung disease

Sulfite-induced protein radical formation in LPS aerosol-challenged mice: Implications for sulfite sensitivity in human lung disease

Exposure to (bi)sulfite (HSO3–) and sulfite (SO32–) has been shown to induce a wide range of adverse reactions in sensitive individuals. Studies have shown that peroxidase-catalyzed oxidation of (bi)sulfite leads to formation of several reactive free radicals, such as sulfur trioxide anion (.SO3–),...

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Bibliographic Details
Main Authors: Ashutosh Kumar, Mathilde Triquigneaux, Jennifer Madenspacher, Kalina Ranguelova, John J. Bang, Michael B. Fessler, Ronald P. Mason
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
(Bi)sulfite
Protein radicals
Lung diseases
Myeloperoxidase and asthma
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717307735

Internet

http://www.sciencedirect.com/science/article/pii/S2213231717307735

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