Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer

Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer

<i>Background and objectives:</i> Cytotoxic T-lymphocyte (CTL)-mediated inflammatory response to tumors plays a crucial role in preventing the progression of some cancers. Programmed cell death ligand 1 (PD-L1), a cell-surface glycoprotein, has been reported to repress T-cell-mediated im...

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Bibliographic Details
Main Authors: Ilknur Calik, Muhammet Calik, Gulistan Turken, Ibrahim Hanifi Ozercan, Adile Ferda Dagli, Gokhan Artas, Burcu Sarikaya
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Medicina
Subjects:
cytotoxic t lymphocytes
colorectal cancer
pd-l1 expression
prognosis
tumor microenvironment
Online Access:https://www.mdpi.com/1010-660X/55/11/723

Internet

https://www.mdpi.com/1010-660X/55/11/723

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