Recombinant SFRP5 protein significantly alleviated intrahepatic inflammation of nonalcoholic steatohepatitis

Recombinant SFRP5 protein significantly alleviated intrahepatic inflammation of nonalcoholic steatohepatitis

Abstract Background Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine modulating metabolism dysfunction. This study aims to observe the effect of recombinant SFRP5 protein on nonalcoholic steatohepatitis (NASH). Methods We set up a prokaryotic expression system and purifi...

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Bibliographic Details
Main Authors: Lili Chen, Xiaolong Zhao, Guangjun Liang, Jiuru Sun, Zhifeng Lin, Renming Hu, Peili Chen, Zhaoyun Zhang, Linuo Zhou, Yiming Li
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Nutrition & Metabolism
Subjects:
SFRP5
Nonalcoholic steatohepatitis
Non alcoholic fatty liver disease
Chronic inflammation
Online Access:http://link.springer.com/article/10.1186/s12986-017-0208-0

Internet

http://link.springer.com/article/10.1186/s12986-017-0208-0

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