A20/TNFAIP3 heterozygosity predisposes to behavioral symptoms in a mouse model for neuropsychiatric lupus

A20/TNFAIP3 heterozygosity predisposes to behavioral symptoms in a mouse model for neuropsychiatric lupus

Background: Neuropsychiatric lupus (NPSLE) refers to the neurological and psychiatric manifestations that are commonly observed in patients with systemic lupus erythematosus (SLE). An important question regarding the pathogenesis of NPSLE is whether the symptoms are caused primarily by CNS-intrinsic...

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Bibliographic Details
Main Authors: C. Daems, M. Sékulic, V. Vulsteke, G. van Loo, R. D’Hooge, Z. Callaerts-Végh, P. Callaerts
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Neuropsychiatric lupus
A20/TNFAIP3
Behavior
Neuroinflammation
Genetic predisposition
Environmental trigger
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354619300183

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http://www.sciencedirect.com/science/article/pii/S2666354619300183

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