Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome.

Nutritional factors play important roles in the etiology of obesity, type 2 diabetes mellitus and their complications through genotype x environment interactions. We have characterised molecular adaptation to high fat diet (HFD) feeding in inbred mouse strains widely used in genetic and physiologica...

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Bibliographic Details
Main Authors: Helen Waller-Evans, Christophe Hue, Jane Fearnside, Alice R Rothwell, Helen E Lockstone, Sophie Caldérari, Steven P Wilder, Jean-Baptiste Cazier, James Scott, Dominique Gauguier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855786?pdf=render