ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.

Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular disease and is characterized by absence of the cytoskeletal protein dystrophin, muscle wasting, and fibrosis. We previously demonstrated that systemic infusion or oral administration of angiotensin-(1-7) (Ang-(1-7)), a pept...

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Bibliographic Details
Main Authors: Cecilia Riquelme, María José Acuña, Javiera Torrejón, Daniela Rebolledo, Daniel Cabrera, Robson A Santos, Enrique Brandan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3973684?pdf=render