The effect of surgical trauma on circulating free DNA levels in cancer patients—implications for studies of circulating tumor DNA

The effect of surgical trauma on circulating free DNA levels in cancer patients—implications for studies of circulating tumor DNA

Detection of circulating tumor DNA (ctDNA) post‐treatment is an emerging marker of residual disease. ctDNA constitutes only a minor fraction of the cell‐free DNA (cfDNA) circulating in cancer patients, complicating ctDNA detection. This is exacerbated by trauma‐induced cfDNA. To guide optimal blood...

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Bibliographic Details
Main Authors: Tenna V. Henriksen, Thomas Reinert, Emil Christensen, Himanshu Sethi, Karin Birkenkamp‐Demtröder, Mikail Gögenur, Ismail Gögenur, Bernhard G. Zimmermann, The IMPROVE Study Group, Lars Dyrskjøt, Claus L. Andersen
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Oncology
Subjects:
bladder cancer
cell‐free DNA
circulating tumor DNA
colorectal cancer
trauma
Online Access:https://doi.org/10.1002/1878-0261.12729

Internet

https://doi.org/10.1002/1878-0261.12729

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