Epigenetic Reprogramming of Human Embryonic Stem Cells into Skeletal Muscle Cells and Generation of Contractile Myospheres

Epigenetic Reprogramming of Human Embryonic Stem Cells into Skeletal Muscle Cells and Generation of Contractile Myospheres

Direct generation of a homogeneous population of skeletal myoblasts from human embryonic stem cells (hESCs) and formation of three-dimensional contractile structures for disease modeling in vitro are current challenges in regenerative medicine. Previous studies reported on the generation of myoblas...

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Bibliographic Details
Main Authors: Sonia Albini, Paula Coutinho, Barbora Malecova, Lorenzo Giordani, Alex Savchenko, Sonia Vanina Forcales, Pier Lorenzo Puri
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000715

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http://www.sciencedirect.com/science/article/pii/S2211124713000715

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