Relevance of STK11 Mutations Regarding Immune Cell Infiltration, Drug Sensitivity, and Cellular Processes in Lung Adenocarcinoma

Relevance of STK11 Mutations Regarding Immune Cell Infiltration, Drug Sensitivity, and Cellular Processes in Lung Adenocarcinoma

Serine/threonine kinase 11 (STK11) is one member of the serine/threonine kinase family, which is involved in regulating cell polarity, apoptosis, and DNA damage repair. In lung adenocarcinoma (LUAD), it can play as one tumor suppressor and always be mutated. In this study, we aimed to assess the rel...

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Bibliographic Details
Main Authors: Zhenqing Li, Bo Ding, Jianxun Xu, Kai Mao, Pengfei Zhang, Qun Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma
STK11 mutation
TCGA
RNA sequencing
bioinformatics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.580027/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.580027/full

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