Co-downregulation of GRP78 and GRP94 induces apoptosis and inhibits migration in prostate cancer cells

Co-downregulation of GRP78 and GRP94 induces apoptosis and inhibits migration in prostate cancer cells

Both glucose-regulated protein 78 kDa (GRP78) and glucose-regulated protein 94 kDa (GRP94) are important molecular chaperones that play critical roles in maintaining tumor survival and progression. This study investigated the effects in prostate cancer cells following the downregulation of GRP78 and...

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Bibliographic Details
Main Authors: Lu Tong, Wang Yue, Xu Kang, Zhou Zhijun, Gong Juan, Zhang Yingang, Gong Hua, Dai Qiang, Yang Jun, Xiong Biao, Song Ze, Yang Gang
Format: Article
Language:English
Published: De Gruyter 2019-07-01
Series:Open Life Sciences
Subjects:
grp78
grp94
prostate cancer
apoptosis
migration
Online Access:https://doi.org/10.1515/biol-2019-0043

Internet

https://doi.org/10.1515/biol-2019-0043

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