Hypermethylation leads to bone morphogenetic protein 6 downregulation in hepatocellular carcinoma.

BACKGROUND: In the liver, bone morphogenetic protein 6 (BMP-6) maintains balanced iron metabolism. However, the mechanism that underlies greater BMP-6 expression in hepatocellular carcinoma (HCC) tissue than adjacent non-cancerous tissue is unclear. This study sought to investigate the epigenetic me...

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Bibliographic Details
Main Authors: Yinghua He, Ying Cui, Baiying Xu, Jun Gu, Wei Wang, Xiaoying Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3907571?pdf=render