PIK3AP1 and SPON2 Genes Are Differentially Methylated in Patients With Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) Syndrome

PIK3AP1 and SPON2 Genes Are Differentially Methylated in Patients With Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) Syndrome

Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is the most common autoinflammatory disease in children and is often grouped together with hereditary periodic fever syndromes, although its cause and hereditary nature remain unexplained. We investigated whether differe...

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Bibliographic Details
Main Authors: Ema Lovšin, Jernej Kovač, Tine Tesovnik, Nataša Toplak, Daša Perko, Tomaž Rozmarič, Maruša Debeljak, Tadej Avčin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
PFAPA
differential methylation
PIK3AP1
SPON2
MSRE-qPCR
MeDIP
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01322/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01322/full

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