Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.

Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.

REG4, which encodes Reg IV protein, is a member of the calcium-dependent lectin superfamily and potent activator of the epidermal growth factor receptor/Akt/activator protein-1 signaling pathway. Several human cancers overexpress Reg IV, and Reg IV expression is associated with intestinal phenotype...

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Bibliographic Details
Main Authors: Yutaka Naito, Naohide Oue, Takao Hinoi, Naoya Sakamoto, Kazuhiro Sentani, Hideki Ohdan, Kazuyoshi Yanagihara, Hiroki Sasaki, Wataru Yasui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487720?pdf=render

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http://europepmc.org/articles/PMC3487720?pdf=render

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