Molecular mechanisms of esophageal epithelial regeneration following repair of surgical defects with acellular silk fibroin grafts

Abstract Constructive remodeling of focal esophageal defects with biodegradable acellular grafts relies on the ability of host progenitor cell populations to repopulate implant regions and facilitate growth of de novo functional tissue. Intrinsic molecular mechanisms governing esophageal repair proc...

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Bibliographic Details
Main Authors: Gokhan Gundogdu, Mehmet Tosun, Duncan Morhardt, Ali Hashemi Gheinani, Khalid Algarrahi, Xuehui Yang, Kyle Costa, Cinthia Galvez Alegria, Rosalyn M. Adam, Wei Yang, Joshua R. Mauney
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86511-9