A Computational Study on Thiourea Analogs as Potent MK-2 Inhibitors

Mitogen-activated protein kinase-activated protein kinase 2 (MK-2) has been identified as a drug target for the treatment of inflammatory diseases. Currently, a series of thiourea analogs as potent MK-2 inhibitors were studied using comprehensive computational methods by 3D-QSAR, molecular docking a...

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Bibliographic Details
Main Authors: Guohui Li, Hongzong Si, Mingjuan Ji, Jieshan Qiu, Ming Hao, Hong Ren, Fang Luo, Shuwei Zhang
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/13/6/7057