Total copy number variation as a prognostic factor in adult astrocytoma subtypes

Total copy number variation as a prognostic factor in adult astrocytoma subtypes

Abstract Since the discovery that IDH1/2 mutations confer a significantly better prognosis in astrocytomas, much work has been done to identify other molecular signatures to help further stratify lower-grade astrocytomas and glioblastomas, with the goal of accurately predicting clinical outcome and...

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Bibliographic Details
Main Authors: Kanish Mirchia, Adwait Amod Sathe, Jamie M. Walker, Yelena Fudym, Kristyn Galbraith, Mariano S. Viapiano, Robert J. Corona, Matija Snuderl, Chao Xing, Kimmo J. Hatanpaa, Timothy E. Richardson
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Acta Neuropathologica Communications
Subjects:
Copy number variation
CNV
Astrocytoma
Glioma
Glioblastoma
GBM
Online Access:http://link.springer.com/article/10.1186/s40478-019-0746-y

Internet

http://link.springer.com/article/10.1186/s40478-019-0746-y

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