Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Sterols are constituents of the cellular membranes that are essential for their normal structure and function. In mammalian cells, cholesterol is the main sterol found in the various membranes. However, other sterols predominate in eukaryotic microorganisms such as fungi and protozoa. It is now well...

Full description

Bibliographic Details
Main Authors: Wanderley de Souza, Juliany Cola Fernandes Rodrigues
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2009/642502