Mechanism of Mitochondrial Connexin43′s Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury

Mechanism of Mitochondrial Connexin43′s Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury

We observed mitochondrial connexin43 (mtCx43) expression under cerebral ischemia-reperfusion (I/R) injury, analyzed its regulation, and explored its protective mechanisms. Wistar rats were divided into groups based on injections received before middle cerebral artery occlusion (MCAO). Cerebral infar...

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Bibliographic Details
Main Authors: Shuai Hou, Ping-Ping Shen, Ming-Ming Zhao, Xiu-Ping Liu, Hong-Yan Xie, Fang Deng, Jia-Chun Feng
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial connexin43
mitochondria
cerebral ischemia-reperfusion
mitochondrial ATP-sensitive K+ channel
protein kinase C
Online Access:http://www.mdpi.com/1422-0067/17/5/679

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http://www.mdpi.com/1422-0067/17/5/679

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