Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model

Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model

Introduction: The clinico-pathological and molecular factors that drive the prognosis of invasive lobular breast carcinoma (ILC) are not entirely explored. In this regard, the development and validation of a prognostic model for ILC and the investigation of the distribution of molecular abnormalitie...

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Bibliographic Details
Main Authors: Luisa Carbognin, Michele Simbolo, Anna Caliò, Caterina Vicentini, Pietro Delfino, Isabella Sperduti, Matteo Fassan, Francesco Schettini, Maria Vittoria Dieci, Gaia Griguolo, Sara Pilotto, Elena Fiorio, Grazia Arpino, Valentina Guarneri, Sabino De Placido, Pierfranco Conte, Erminia Manfrin, Matteo Brunelli, Giovanni Scambia, Aldo Scarpa, Giampaolo Tortora, Emilio Bria
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Breast
Subjects:
Breast cancer
Lobular
Prognosis
Next-generation sequencing
Transcriptome analysis
CDK4
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977620300357

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http://www.sciencedirect.com/science/article/pii/S0960977620300357

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